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Synthesized in the intestinal L-cells, GLP-1 is secreted in response to food intake, stimulating insulin secretion and inhibiting glucagon release [1]
Through simulation of the viral biomass reaction, important factors influencing viral replication can be identified, such as essential enzymes or the availability of specific nutrients 17
This characteristic limits its action primarily to the receptors with which it interacts, specifically the GLP-1 receptors in the pancreas and brain, which are involved in regulating blood sugar levels and appetite
Despite the lack of clear mechanistic insights, both classes of drugs are widely used in diverse clinical contexts, and clinical guidelines strongly suggest their use especially in patients at higher cardiovascular risk