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It's important to note that GLP-1 receptor agonists are associated with an increased risk of gallbladder and biliary disorders, including cholelithiasis (gallstones) and cholecystitis (gallbladder inflammation), as documented in their Summary of Product Characteristics

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Conclusions Following the initiation of semaglutide, other GLP-1 agonists, or GLP-1/GIP dual agonists, practitioners should be aware of the potential severe complications, such as colonic ischemia, and properly educate their patients about these risks

Among them, Prevotella , unclassified S24.7, Mucispirillum , Dehalobacterium , Ruminococcus , unclassified Peptococcaceae , Coprobacillus , Bilophila , Desulfovibrio , and Anaeroplasma were differential gut microbiota biomarkers for soybean oil