It is important to distinguish between a temporary bubble caused by normal medication deposition and other injection site reactions such as localised inflammation, infection, or allergic response
The 1.5 mg dosage formulation of dulaglutide was the most common at each timepoint of interest
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Insulin Sensitivity Improvements in insulin resistance were greater at 24 and 48 weeks
Common Side Effects When side effects occurred, they were typically mild, transient, and similar in frequency to placebo groups: Reported Adverse Effects Most Common (occurring in small percentage of participants): Mild to moderate headaches (most frequently reported, often resolving with continued use) Injection site reactions (minor redness, swelling, or irritation at injection site) Gastrointestinal effects (particularly at higher oral doses: mild nausea, diarrhea, flatulence) Fatigue (reported occasionally during initial adaptation period) Rare Events: One case of chest tightness was deemed possibly related to treatment in safety trials
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