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It really highlights the need for further investigation into their ocular safety profile, first study author Reut Shor, MD, of the Department of Ophthalmology and Vision Sciences at the University of Toronto, Canada, told Healthline

The combination of medication-induced delayed gastric emptying plus alcohol-induced inflammation creates a perfect storm of gastrointestinal distress

10.1001/jamaophthalmol.2024.2296

Two weeks before your last dose Drop carbohydrates to 20 to 30 grams per day

Some attenuation in HR was observed, but the impact of triple combination therapy on MACE, HHF, and CKD progression was still consistent, assuming 50% additivity