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They help with weight loss by reducing ones appetite and increasing the feeling of being full, slowing digestion, and reducing what some refer to as food noise. GLP-1s are a valuable, proven tool when part of a weight-management program that includes lifestyle changes such as healthier eating and increased activity
In contrast to the CV outcomes trials with GLP-1RAs, those with DPP-4 inhibitors demonstrated consistent non-inferiority in both the primary composite outcome and individual components compared to placebo, and even showed some unexpected increases in risk of hospitalization for HF, acute pancreatitis, and hypoglycemia [31,32,33,34]
Subscribers to GoodRx for Weight Loss can access FDA-approved, brand-name GLP-1 medications