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There are very few options today for orally delivered GLP-1 drugs

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HIF-1 stabilization/upregulation is associated with increased expression of vascular endothelial growth factor (VEGF) (Mu et al., 2003

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SGLT-2 Inhibitors (e.g., canagliflozin, dapagliflozin): These medications help eliminate glucose through urine, offering a viable alternative for those who cannot tolerate GLP-1 receptor agonists