Share: The popularity of GLP-1 medications such as semaglutide (Ozempic, Wegovy, and Rybelsus) and tirzepatide (Mounjaro and Zepbound) has dramatically reshaped the way obesity is treated
(Many people hold a pen this way when they write)
Increasing evidence suggests a strong pathophysiological connection between AD and Diabetes Mellitus Type II (DM2), which is characterized by insulin resistance and subsequent pancreatic islet -cell failure, leading to insufficient insulin levels for normal glucose metabolism 3,4,5,6
It mimics a natural hormone called glucagon-like peptide-1 that your gut produces after eating
Similarly, people's bodies can adjust to GLP-1 doses, meaning the drug becomes less effective over time and the dose must be nudged to produce the desired amount of "hunger noise" reduction