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Semaglutide, like other GLP-1 agonists, is a valuable medication in the treatment of type 2 diabetes and obesity and is increasing in popularity

Details for certainty of evidence assessment: (a) the study with the reported larger effect was chronologically first (publication bias)

In these trials, significant weight loss was demonstrated with liraglutide 3.0 mg therapy, compared to placebo (8.0% in SCALE obesity and prediabetes, 6.0% in SCALE-diabetes)

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The peptide is intended solely for basic research and the structural characterization of metal-binding peptide complexes