Instead of universal withholding, the guidance emphasized shared decision-making and targeted risk reduction for patients most likely to have delayed gastric emptying, such as those in the dose-escalation phase, those with notable gastrointestinal symptoms, those on higher doses, and those with comorbid conditions that slow gastric emptying
Moxibustion can downregulate p53 and ROS, upregulate SLC7A11, GPX4 expression, and reduce ferroptosis
In addition, mitochondria lack more advanced repair pathways, such as nucleotide excision repair and homologous recombination, which makes mtDNA particularly susceptible to the accumulation of mutations [35], which leads to a higher rate of damaged mtDNA in mitochondria and further aggravates oocyte damage
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The experiment was conducted with two glucose concentrations: 0.5% and 5%, which promoting a respiratory and fermentative metabolism, respectively [18]