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Besides their enzymatic activity, cytosolic GSTs (such as class Alpha) exhibit an ability to bind various hydrophobic ligands (xenobiotics as well as hormones) and thus contribute to their intracellular transport and disposition

Multiple patient reviews specifically call this out as a differentiator

However, its oral bioavailability is limited 234 , and the presence of specific transporters that allow it to cross the BBB, in addition to passive diffusion, remains to be conclusively demonstrated

doi: 10.3390/biomedicines11030653 81 ParkJSLeeEJLeeJCKimWK

They also help with other issues, including sleep apnea, kidney problems, heart disease, and fatty liver disease