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Common: Nausea, vomiting, diarrhea, or constipation Reduced appetite (sometimes too much) Mild low blood sugar (especially with other diabetes medications) Injection site reactions Less common but serious: Pancreatitis Gallbladder issues Kidney complications from dehydration Thyroid tumors (observed in rodent studies and still under investigation in humans) This is a non-exhaustive list

Clinical assessment and full blood count showing macrocytic anaemia are also important, though neurological symptoms can occur without haematological changes

Timely delivery is important for research continuity and project timelines

Monotherapy profile Cagrilintide as a standalone compound shows a remarkably favorable tolerability profile

GLP-1 drugs already lower glucose levels by enhancing insulin secretion