Stress triggers stress hormones that make your body want to hold onto fat, and poor quality or insufficient sleep puts your body into a state of chronic stress
A comprehensive approach may include both strategies: dietary optimization with low-glycemic sweeteners alongside pharmacological support when indicated
Key Variables That Influence Your Actual Weight Loss Outcome Your weight loss on GLP-1 medication depends on factors beyond dose: baseline metabolic rate, insulin sensitivity, genetic predisposition to appetite regulation, diet quality, physical activity, medication tolerance, and adherence consistency
Key metabolic hormones (including glucagon-like peptide-1 (GLP-1), leptin, ghrelin, and cholecystokinin (CCK) play dual roles: not only regulating hunger and metabolism, but also directly modulating the activity and expression of taste receptors throughout the oral cavity and gastrointestinal tract
2 While physicians are excited to have an effective tool for patients struggling with obesity, many are concerned with the long-term use of these drugs, noting side effects and cost are top reasons for patients who discontinue treatment
