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159 Multiple Wnt/-catenin signalling-related genes are hypermethylated in the brains of PD patients, including its receptor LRP5, the transcription factor TCF7L2, the inhibitors FRZB, SFRP1, and SFRP2, and multiple target genes

Furthermore, NAC affects various neurotransmitter systemsincluding glutamatergic, dopaminergic, GABAergic, serotonergic, cholinergic, and adrenergic pathwaysby modulating synaptic transmission, receptor activity, and transporter functionality

Drug repositioning for Fabry disease: acetylsalicylic acid potentiates the stabilization of lysosomal alpha-galactosidase by pharmacological chaperones

7 Copper-tripeptide complexes stimulate dermal papilla cell proliferation and shift these cells toward survival by raising the Bcl-2/Bax ratio and reducing apoptosis markers