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Symptoms of lactic acidosis may include feeling unwell, stomach and muscle pain, difficulty breathing, and sleepiness

& Gladman, D

When the incretin hormone glucagon-like peptide-1 (GLP-1) was subsequently shown to account for up to 70% of insulin secretion in response to nutrient intake (2), its potential as a therapeutic target in type 2 diabetes (T2D) was realized

The interindividual variability was, however, greater for dulaglutide (40.5% coefficient of variation (CV) for CL) compared to semaglutide (CV for CL was 15.2% in the present analysis and 12.9% in the phase 3 analysis [6])

These agents may improve erectile function by enhancing glycaemic control, reducing weight, and improving vascular health