The effect of berberine supplementation on obesity indices: A dose- response meta-analysis and systematic review of randomized controlled trials
Since control of diabetes and obesity are significant health outcome risk factors, it is conceivable that the shortages and high cost of GLP1 agonists will exacerbate existing health disparities. David Cutler, MD His perspective echoed what Ma told us, namely that [o]ne of the biggest bottlenecks with GLP-1RA access is cost and insurance. Even if a doctor prescribes [this type of drug], patients cannot obtain it if their insurance does not cover it, which could worsen disparities, especially for those with public insurance or in underserved populations, he also emphasized
Meta-analyses on gray and white matter changes in T2DM patients with cognitive impairment have concluded that T2DM impairs cognitive function by affecting specific brain structures (Ma et al., 2022)
This dual action helps normalize blood glucose levels without causing significant hypoglycemia in most patients, though the risk increases when combined with insulin or sulfonylureas
Ongoing research continues to refine our understanding of these medications