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Given at higher doses than in diabetes treatment, GLP-1 analogues are now routinely licensed for the treatment of obesity, for example high-dose Liraglutide 3 mg daily (43) and Semaglutide 2.4 mg weekly (44)

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Achieving a stable and euthyroid (normal thyroid function) state is important because untreated or undertreated hypothyroidism can blunt the metabolic benefits of GLP-1 medications, such as weight loss and improved blood sugar control