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This makes it especially interesting for: Midlife weight gain Menopause-related metabolic decline Andropause-related fat gain Insulin resistance PCOS/PMOS Visceral fat accumulation MOTS-c & Sarcopenia: Can It Help Preserve Muscle With Aging

The confusing part about those studies is that there are not much of these drugs that actually get into the brain

Therefore, the findings are not completely consistent across species, likely because humans are long-lived while mice have much shorter lifespans, resulting in different disease time courses and inflammatory milieu