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In a 46-week obesity treatment trial, mean weight loss was 14.9% at the highest dose

Contraindications remain somewhat speculative given limited human data

Mathieu C, Dandona P, Gillard P et al (2018) Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (the DEPICT-2 Study): 24-week results from a randomized controlled trial