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51,52 Although our preclinical studies mostly employed male mice, this choice was made to minimize variability, particularly because MAOB is located on the X chromosome, making males a more straightforward model for assessing MAOB effects without the potential confound of X-inactivation

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These signaling molecules activate biological pathways, which cells have used to respond to trauma, injury, and surgical metabolic stress

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Further studies have identified several genes with nucleotide or amino acid sequences that are similar to the most traditional -glutamyl transferase, the gene symbol of which has been systematically designated as GGT1