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However, there are multiple cases of valproic acid-induced hyperammonemia reported in older male patients with both chronic valproic acid use and recent initiation

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Important Caveats: This observation is anecdotal, not registry-derived It is not a substitute for controlled epidemiology It provides real-world context consistent with MTC rarity and absence of compelling causal signals in highest-quality human evidence Clinical Significance: In a practice seeing more thyroid cancer than anywhere globally, we are not observing an MTC wave in GLP-1 users

Before I could find another source I gained back 20# in 3 weeks, the first 7 days, without changing my eating, I gained a pound a day