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Moreover, Lip-1 reduced microglial activation and the secretion of pro-inflammatory cytokines such as IL-6 and TNF-, while mitigating oxidative stress, lipid peroxidation, mitochondrial damage and neuronal injury following LPS exposure
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In naturally aged mice, FOXO4-DRI improved the testicular microenvironment and alleviated age-related testosterone secretion insufficiency with decreased p53, p21, and p16 protein levels in treated testes compared to aged controls
Further research should evaluate whether TB or STLs demonstrate superior stability and therapeutic advantages