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African children receiving HU at a dosage of 20 mg/kg/d in Uganda, a nation with a high malaria incidence, are safe to Opoka et al

Regular monitoring of weight, blood pressure, and metabolic parameters is recommended throughout treatment

Recent research provided a deeper understanding of this notion, revealing that carbohydrate metabolism could adapt to the hypoxia condition in mild preeclampsia while a decompensation of carbohydrate metabolism reprogramming was discovered in severe preeclampsia (11) (Figure 2)

The accumulation of free radicals over the years can accelerate the aging process

Eur J Nucl Med Mol Imaging 48:28232833 Guntur VP, Nemkov T, de Boer E, Mohning MP, Baraghoshi D, Cendali FI, San-Millan I, Petrache I, DAlessandro A (2022) Signatures of mitochondrial dysfunction and impaired fatty acid metabolism in plasma of patients with post-acute sequelae of Covid-19 (PASC)