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Epub 2008 Oct 1

Patients with specific genetic patterns may experience fewer side effects or require different dosing schedules

500 solutions of Norleual, D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 , piroxicam, verapamil and 7-ethoxycoumarin (low, moderate and highly metabolized controls, respectively) were prepared in acetonitrile

JAMA 303, 235241

Gupta and colleagues 36 were the first to report GLP-1 receptor expression in human hepatocytes and proposed that they play a direct role in reducing hepatic steatosis in vitro through the modulation of effectors of the insulin signaling pathway