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This low-grade, long-term inflammation spreads throughout the body, irritating joint linings, breaking down cartilage matrix integrity, and hyper-sensitizing local nerve pathways

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Compounded medications vary in quality, consistency and composition, and theyre not subject to the same rigorous testing as FDA-approved formulations, said Korman

Symptoms may include yellowing of the skin and eyes, itching, dark colored urine, stomach pain and tender liver (indicated by pain under the front of the rib cage on the right side), sometimes with loss of appetite

Choose a medication you can afford, tolerate, and access for the long term