Other documented adverse effects include injection site reactions, fatigue, dizziness, and headache
This continuity helps your body adapt predictably as the dose grows stronger, and your healthcare provider can more easily assess side effects and efficacy
But retatrutide may be even more effective , for several reasons: Glucagon receptor activation promotes hepatic fat oxidation Reduces liver fat accumulation more robustly Improves liver enzyme levels (ALT, AST) In a subgroup analysis of the retatrutide Phase 2 trial: Patients with suspected NAFLD showed a 70%+ reduction in liver fat content , measured by MRI-PDFF These effects surpassed the reductions seen with tirzepatide and semaglutide in comparable studies Another study showed that 93% of patients on the highest dose of retatrutide had 100% resolution of fatty liver
The following are some known safety considerations that a prescribing healthcare provider will monitor for in patients taking semaglutide
Fatigue Interestingly, few of the major trials investigating the impact of Ozempic on weight loss and health report fatigue, tiredness, or lethargy as potential side effects