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Although, the present study did not provide evidence for the involvement of Epac in OA- mediated PI hydrolysis, demonstration of Epac2 expression in STC-1 cells and published reports in other cell types support our conclusion about the role of Epac/PLC- pathway in Ca 2+ mobilization

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In studies employing this approach, the risk of cancer progression and recurrence triggered by senescent cancer cells was significantly mitigated 63

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