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Figure 5 Understanding the balance between GIP receptor signaling, intracellular recycling, and desensitization is crucial for interpreting the physiological consequences of a given compound

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In fact, GIP infusion actually reverses the hypophagic effect of native GLP-1 infusion [11], although this may be attributable to an anti-nauseating effect of GIPR agonism that has recently been described [13,14,15]

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