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Apoptosis is initiated by caspase-9 and caspase-8, leading to DNA cleavage and fragmentation (Babalghith et al., 2022)

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Fatigue and weakness affect approximately 110% of patients taking Ozempic (semaglutide), a GLP-1 receptor agonist licensed in the UK for type 2 diabetes

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This finding suggests that DPP4 inhibitors, owing to their GLP-1-enhancing actions, may have a direct beneficial effect on cardiomyocyte function