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By improving blood sugar control, reducing blood pressure, and potentially exerting direct anti-inflammatory effects on the kidneys, these drugs can help preserve vital kidney function

The administration of hemin results in the boost of HO-1 expression and mitigates inflammatory responses in retinal ganglion cell injury in diabetic retinopathy, as well as diabetic wound healing, diabetic kidney function and [54,55,56]

This setup gives researchers a practical way to study angiogenic upregulation, cytoskeletal dynamics, and extracellular matrix (ECM) remodelling all at once, rather than running separate isolated assays

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