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Medical advice should be sought if severe pain, urinary symptoms, or dehydration occur

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The shedding typically begins three to six months after the onset of rapid weight loss and resolves within six to twelve months as the body adapts to its new metabolic equilibrium

American College of Gastroenterology Clinical Guideline: Diagnosis and Management of Gastroparesis

In contrast, concerning signs include spreading redness, increasing warmth, severe pain, discharge from the injection site, or systemic symptoms such as fever, which could indicate infection