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Moreover, this pathway promotes the polarization of macrophages towards an M1-type pro-inflammatory phenotype, thereby playing a crucial role in anti-infective immunity and inflammatory responses

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Individually, semaglutide has been found to be noninferior to placebo when examining rates of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in patients with type 2 diabetes at high cardiovascular risk 18,19