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Nrf2is a key factor in the control of the expression of genes involved in the regulation of oxidative stress, via the enhanced production of cellular antioxidants

Given that NADPH is reduced by Dox treatment (Fig

Dose adjustments may be necessary based on patient response, tolerance, and individual treatment goals, as determined by the patients physician

Participants given the highest dose lost around 20 pounds in 12 weeks, and others lost inches from their waist in 6 months