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Tesofensine is a triple monoamine reuptake inhibitor, raising dopamine, serotonin, and noradrenaline to reduce appetite
Essential because we need to obtain this from our diet, and water soluble because it is readily absorbed in water and into tissues for immediate use (as opposed to fat soluble vitamins which are stored in the body)
Because the fatty tissue has fewer blood vessels than muscle, the absorption is more of a steady trickle than a rush
Nasal Spray: For those who prefer a non-invasive option, PT-141 is also available as a nasal spray
Fang EF, Hou Y, Palikaras K, Adriaanse BA, Kerr JS, Yang B, Lautrup S, Hasan-Olive MM, Caponio D, Dan X, Rocktschel P, Croteau DL, Akbari M, Greig NH, Fladby T, Nilsen H, Cader MZ, Mattson MP, Tavernarakis N, Bohr VA (2019) Mitophagy inhibits amyloid- and tau pathology and reverses cognitive deficits in models of Alzheimers disease
