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MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

However, additional studies with larger sample sizes and longer duration are necessary to evaluate the exact effect of these MNs among special high-risk groups in the prevention of DILI

(II) The gamma-glutamylcysteine synthetase enzyme is the main rate-limiting step in this cycle, and this reaction is non-allosterically inhibited by physiologic concentrations of glutathione

393 Nevertheless, statins have been shown to have beneficial effects on arterial elasticity in different meta-analyses