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Output from the EXAMS II fate model using the same application scenario produced estimated water concentrations which closely corresponded to the measured ones

Core Mechanisms Recap: NNMT Inhibition: Prevents NAD depletion, supporting energy production and metabolic flexibility

Acute Metabolic Effects: Increased Energy Expenditure and Fat Oxidation Mechanism Snapshot Chronic Mechanism: Upregulation of 3-AR expression in adipose tissue may underlie the enhanced lipolysis and reduced fat mass observed with long-term treatment

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