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A heritable switch in carbon source utilization driven by an unusual yeast prion

The antioxidant solution was prepared as follows: a stock solution containing 4% ascorbic acid (VWR, Leuven, Belgium), 0.4% glutathione and 2% uric acid (Sigma-Aldrich, Lyon, France) was prepared in distilled water and filtered using a 0.2 m filter after adjusting the pH to 7.5 with 10 M KOH

Starting at low doses (0.25 mg) and titrating gradually minimizes gastrointestinal distress