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2 Interactions between the GLP-1 pathway and alcohol As shown in Figure 1, the accumulated preclinical findings imply that the GLP-1 pathway modulates alcohol-mediated responses, which include the following: 1) alcohol drinking, 2) alcohol-induced behaviors and neurochemistry, 3) the motivation to consume alcohol and alcohol-seeking, and 4) relapse drinking

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The communication between gut microbiota and the central nervous system (CNS) is facilitated by neuroactive substances produced by the former through the vagus nerve (Tan et al., 2022)

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