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The Numbers That Matter: In the landmark SURMOUNT-5 trial published in the New England Journal of Medicine in May 2025, participants taking tirzepatide lost an average of 20.2% of their body weight over 72 weeks, compared to 13.7% with semaglutide

"I was so depressed about becoming a father, not knowing how to be a father, not knowing if my daughter would be comfortable around me," he tells PS

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Effect of database profile variation on drug safety assessment: an analysis of spontaneous adverse event reports of Japanese cases

However, while these initial findings are promising, it is crucial to understand the risks and side effects associated with semaglutide