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Figure 1 Regarding cations, why do anomalies in sodium and calcium channels cause such similar disorders

2a) and its release in the supernatant was observed when the cells were exposed to APAP for 24 hours in a dose-dependent manner as shown in Fig

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Key gaps to address: dose-response in humans, safety/tolerability profiles across populations, interaction effects in stacks, and long-term cardiometabolic outcomes