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These provide measurable confirmation beyond subjective assessment

Identification of a targeted ACSL4 inhibitor to treat ferroptosis-related diseases

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Biochimie 108 , 4047 (2015)

Although the use of targeted metabolite tracing, such as deuterium tracing of NADPH [7], is successful and remains the gold standard in the field, this approach requires mass-spectrometry, which may not be accessible to many laboratories