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cultured insulin-sensitive human HepG2 cells under high-glucose conditions and administered cocoa-derived polyphenols and epicatechin, which blocked tyrosine phosphorylation and lowered total IR, IRS-1, and IRS-2 levels through PI3K/AKT and AMPK pathway inhibition, thereby mitigating high-glucose-induced insulin signaling impairment that alters gluconeogenesis (Mary et al., 2002)

The same applies to the rest of our lineup

But you dont need to go to a doctors office

This dual action maintains glucose stability

The recommendation is to start with a lower concentration and gradually increasing usage can help minimize these risks