what is the difference between semaglutide and glp-1 Comparing Ozempic, Wegovy Other Drugs Liraglutide vs Semaglutide: Comparing Weight

LS-mean change from baseline in HOMA-IR and TyG index showed significantly greater degree of reduction in high GLP-1 compared with low GLP-1 groups [between group difference -3.14 (95% CI -6.19, -0.100) and between group difference -0.57 (95% -1.05, -0.09) respectively]

[DOI] [PubMed] [Google Scholar] 52.Gnaiger E

[7] Because testosterone and its metabolites could be excreted into breast milk and might suppress lactation or adversely affect a nursing infant, therapy is likewise contraindicated during breastfeeding and should not be used in women for routine androgen replacement

This treatment mimics GLP-1 (glucagon-like peptide-1), a natural hormone that regulates appetite and blood sugar levels

What can be emphasised is the spread of effects across organs, and additional effects are continuously being observed and investigated