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Receptor binding triggers a Gs-cAMP-PKA signaling cascade leading to GH synthesis and pulsatile release

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Post hoc analyses explored changes in body weight from baseline to week 120 and in a variety of participant subgroups (from baseline to week 68 and week 120, and from week 68 to week 120), and the proportion of participants with 5% or higher weight loss from baseline at week 120