If a patient does not tolerate the 2.4 mg once-weekly maintenance dose, the dose may be reduced to 1.7 mg once weekly
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These tactics aim to minimize gastric distension and chemical irritation that provoke nausea while supporting overall tolerability and continuation of therapy
There is some intriguing data suggesting that GIP, at least in animals, mitigates some of the adverse events that can be induced by GLP-1, says Drucker
It was also noted that in comparison to a 1.2 mg dose of the active control, doses of semaglutide ranging from 0.8-1.6 resulted in a greater reduction in fasting plasma glucose
