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While much of the early data comes from animal studies, the interest in human applications has grown

HGF protects neurons and promotes their survival via anti-apoptotic, anti-fibrotic, anti-inflammatory, pro-angiogenic, and immune-modulatory actions

NAD+ is a critical coenzyme involved in hundreds of enzymatic reactions including glycolysis, the citric acid cycle, and oxidative phosphorylation, as well as serving as a substrate for NAD+-consuming enzymes including sirtuins, PARPs, and CD38