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If you're still anxious, here are a few tips that research suggests can help make injections more comfortable: Let the pen warm up: Allowing the pen to sit at room temperature for 30 minutes can help reduce any stinging sensation from the cold liquid

I haven't had any weight loss so I don't think it's due to that." Swelling may be reduced by massaging the breasts to increase circulation, said Levine, who also recommends ibuprofen, Tylenol or a cool compress to relieve symptoms

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Always choose a different spot each time and make sure the area is clean and dry