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Methods: A systematic search of PubMed, Web of Science, and Scopus was conducted until December 2024

2020;doi: 10.2337/dc19-1350), which examined the initiation of combination therapy with exenatide once-weekly (Bydureon, AstraZeneca) plus dapagliflozin (Farxiga, AstraZeneca) vs

Patients should talk with their clinician if pregnancy is planned or suspected

The preferred timing is at bedtime to align with natural HGH peaks, often on an empty stomach

For individuals seeking meaningful appetite control and metabolic support, prescription GLP-1 therapy offers a scientifically validated alternative backed by large-scale clinical trials