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However, the wider credible intervals in this NMA resulted in a non-significant result for weight reduction

$0 until approved Price stays the same no matter the dose Clinically studied results About 14% average body weight loss* A once-weekly GLP-1 treatment studied alongside lifestyle support

Taken once weekly

3 The pharmacokinetic feasibility gate: exposure, half-life, and the accumulation requirement The central determinant of whether an orally administered peptide achieves therapeutic systemic exposure is not the sophistication of the delivery platform, but the relationship among absorption rate, elimination half-life, and dosing interval

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