This peroxidase uses the antioxidant tripeptide glutathione (GSH) instead of thioredoxin as the physiological reductant to reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or to hydrolyze the sn-2 ester (alkyl) bond of phospholipids (phospholipase A(2) [PLA(2)] activity)
9 The mechanism for the nasopharyngitis is unknown, but the intensity, duration, and recurrence rate was the same as the placebo group, and this did not cause discontinuation from the clinical trial
Studies have shown that cyclooxygenase (COX) inhibitors, such as aspirin, ibuprofen, and indomethacin, combined with fluconazole can significantly reduce Candida adhesion and biofilm development and increase fluconazole susceptibility
Loss of NRF2 function exacerbates the pathophysiology of sickle cell disease in a transgenic mouse model
Patients need a prescription from a licensed provider