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The most significant concern relates to fluid balance and kidney function monitoring

Methods This randomised, placebo-controlled, double-blinded, phase 2 clinical trial was conducted at two public hospitals in Denmark

Semaglutide, a medication often used for weight loss or diabetes management, can cause fluid loss, which may lower blood pressure and disrupt the balance of bodily fluids, resulting in dizziness

This binding extends its half-life dramatically, which is why a single weekly injection maintains therapeutic levels for seven full days